今日药学

2011, v.21(06) 328-329+344

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枇杷叶紫珠化学成分研究
Chemical Constituents of Callicarpa konchiana

何泽民,林朝展,王姿媛,祝晨蔯
HE Ze-min1,LIN Zhao-zhan2,WANG Zi-yuan3,ZHU Chen-chen2(1.Guangdong Kangyu Pharmaceutical Company

摘要(Abstract):

目的研究枇杷叶紫珠(Callicarpa konchiana)的化学成分。方法应用多种色谱方法进行分离纯化,并根据理化性质和波谱数据进行结构鉴定。结果从枇杷叶紫珠的正丁醇萃取部位分离得到3个化合物,分别为:芹菜素-6,8-二-C-β-D-葡萄糖(ap igen in-6,8-d i-C-β-D-glucopyranosideⅠ)、山奈酚-7-O-β-D-葡萄糖苷(Kaempferol-7-O-β-D-glucopyranosideⅡ)、夏枯草苷(Pruvu loside AⅢ)。结论化合物Ⅰ~Ⅲ均为首次从紫珠属中分离得到。
Objective To studuy the chenmical constituents of Callicarpa konchiana.Methods Isolation and purification were carried out by varied chromatographies,and structure identification of compounds were carried out by physical methods,chenmical methods and spectral data.Results Six compounds were obtained from the n-butanol fraction of C.konchiana,and were identified as apigenin 6,8-di-C-β-D-glucose(Ⅰ),Kaempferol-7-O-β-D-glucopyranoside(Ⅱ),Pruvuloside A(Ⅲ).Conclusion Compounds Ⅰ~Ⅲ are obtained from Callicarpa L.for the first time.

关键词(KeyWords): 枇杷叶紫珠;化学成分
Callicarpa konchiana;chemical constituents

Abstract:

Keywords:

基金项目(Foundation): 国家自然科学基金资助项目(编号:81001613/H2803)

作者(Author): 何泽民,林朝展,王姿媛,祝晨蔯
HE Ze-min1,LIN Zhao-zhan2,WANG Zi-yuan3,ZHU Chen-chen2(1.Guangdong Kangyu Pharmaceutical Company

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