今日药学

2015, v.25(12) 863-867

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IL-1β与糖尿病及糖尿病视网膜病变的相关研究进展
Research Progress of IL-1 with Diabetes Mellitus and Diabetic Retinopathy

田驰,拱梅芳,孙天宇,孙明杰
TIAN Chi,GONG Meifang,SUN Tianyu,SUN Mingjie

摘要(Abstract):

糖尿病视网膜病变(diabetic retinopathy,DR)是糖尿病(diabetes mellitus,DM)最严重的并发症之一,具有很高的致盲率。DR发病机制复杂,至今未明。本文对白细胞介素IL-1β(Interleukin-1,IL-1β)在DR、DM中的作用和IL-1β对与DR发病过程中其他炎症因子的影响做一综述。
Diabetic retinopathy is one of the most severe diabetes complications with a high rate of blindness. The mechanism underlying the development of diabetic retinopathy is extremely complicated,and has not been elucidated yet. Here,we reviewed the role of interleukin-1β and the implication of the other inflammation factors during the progress of diabetes mellitus and diabetic retinopathy.

关键词(KeyWords): 糖尿病;糖尿病视网膜病变;IL-1β;药物研发
diabetes;diabetes retinopathy;interleukin-1β;drug development

Abstract:

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作者(Author): 田驰,拱梅芳,孙天宇,孙明杰
TIAN Chi,GONG Meifang,SUN Tianyu,SUN Mingjie

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