今日药学

2019, v.29(02) 116-119

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1例急性颈内动脉夹层致脑梗死后继发颅内出血的抗栓药物使用分析
Analysis of Antithrombotics Use in One Case of Intracranial Hemorrhage Following Cerebral Infarction Caused by Acute Internal Carotid Artery Dissection

肖昌琼;陈碧;
XIAO Changqiong;CHEN Bi;Department of Phamacy,Center Hospital Medical District of Chenzhou NO.1 People's Hospital;

摘要(Abstract):

目的阐明1例急性颈内动脉夹层致脑梗死后继发颅内出血的抗栓药物使用分析。方法针对患者病情、临床症状、体征以及检验检查结果,查阅最新指南以及相关文献对该例病例进行用药分析,并结合临床进行用药指导。结果本例患者经过静脉溶栓以及血管内介入治疗后继发颅内出血,合并使用抗栓药物治疗并未加重其出血。结论脑梗死后继发出血关键时刻的处理取决于对于患者临床症状的熟悉程度以及患者利益-风险获比的权衡,临床药师需对此进行评估并作出个体化给药方案。
OBJECTIVE To analyze antithrombotics use in one case of intracranial hemorrhage following cerebral infarction caused by acute internal carotid dissection. METHODS According to the patient ' s condition,clinical symptoms,signs and test results,we consulted the latest guidelines and related literature to analyze the medication of this case,and then guidance on medication in combination with clinical practice. RESULTS In this case, intracranial hemorrhage which was secondary to intravenous thrombolysis and intravascular interventional therapy,was not aggravated after application of antithrombotics. CONCLUSION The management of the critical moment of hemorrhage after cerebral infarction depends on the familiarity with the clinical symptoms of patients and the trade-off between the benefit and risk of patients. Clinical pharmacists need to evaluate this and provide personalized medication regimen for the patients.

关键词(KeyWords): 颈内动脉夹层;脑梗死;颅内出血;抗栓药物
internal carotid dissection;cerebral infarction;intracranial hemorrhage;antithrombotics

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基金项目(Foundation): 郴州市第一人民医院科研项目(N2015-013)

作者(Author): 肖昌琼;陈碧;
XIAO Changqiong;CHEN Bi;Department of Phamacy,Center Hospital Medical District of Chenzhou NO.1 People's Hospital;

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