今日药学

2015, v.25(05) 343-346

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广州地区2家精神病专科医院2010~2014年抗精神病药利用评价
Review of Antipsychotic Drugs Utilization in Two Major Psychiatric Hospital in Guangzhou During 2010-2014

陈金兰,张明,李龙霞,温雅
CHEN Jinlan,ZHANG Ming,LI Longxia,WEN Ya

摘要(Abstract):

目的以广州地区2家精神病专科医院为代表,评价抗精神病药的应用状况及趋势。方法采用世界卫生组织推荐的以限定日剂量为指标的药物利用研究方法,对2家医院2010~2014年抗精神病药的使用金额、用药频度、序号比进行统计、分析。结果抗精神病药总消耗金额及用药频度均呈增长趋势,5年增长率分别为51.71%、20.84%;新型非典型抗精神病药消耗金额和用药频度均逐年增加;氯氮平及典型抗精神病药则逐年减少。结论奥氮平、利培酮、喹硫平、阿立哌唑为精神分裂症患者首选药物,同步性较好,使用合理。
OBJECTIVE To evaluate the condition and trend of antipsychotic drugs application,as represented by the 2 major psychiatric hospitals in Guangzhou. METHODS Using the drug utilization review which defined daily dose was recommended as indicator by WHO,the antipsychotic drugs' consumption sum,DDDs,and serial number ratio were counted and analyzed in the 2psychiatric hospitals during 2010-2014. RESULTS The total consumption sum and DDDs of antipsychotic drug showed the tender of growth,5 years growth rates were 51. 71%,20. 84%; The consumption sum and DDDs of new atypical antipsychotic drug increased year by year; while those of chozapine and typical antipsychotics were declining. CONCLUSION Olanzapine, risperidone,quetiapine,aripiprazole are the first choice for patients with schizophrenia,and their application is rational with good synchronism.

关键词(KeyWords): 抗精神病药;限定日剂量;用药频度;用药金额
antipsychotic drugs;defined daily dose(DDD);DDDs;consumption sum

Abstract:

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基金项目(Foundation): 广东省科学技术厅科技计划项目(粤科规划字[2013]137号)111号

作者(Author): 陈金兰,张明,李龙霞,温雅
CHEN Jinlan,ZHANG Ming,LI Longxia,WEN Ya

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