赵路,董栋,雷伟
ZHAO Lu,DONG Dong,LEI Wei

• 1:郑州市妇幼保健院药剂科

摘要(Abstract)：

目的探讨皮质固醇类激素在化脓性脑膜炎中的应用,为临床合理用药提供参考。方法回顾性分析1例5月龄化脓性脑膜炎男性患儿的病例,分析及评价皮质固醇类激素——地塞米松在化脓性脑膜炎治疗中的使用指征、剂量及疗程等问题。结果皮质固醇类激素不应常规用于化脓性脑膜炎的治疗,确有用药指征时,应权衡利弊正确使用,地塞米松的用药剂量推荐为0.15 mg·kg~(-1),ivgtt,q6h,疗程控制在2~4 d,于抗菌药物治疗前或同时使用。结论临床应高度重视皮质固醇类激素在化脓性脑膜炎治疗中的作用,加强临床观察,确保用药安全。
OBJECTIVE To discuss the application of cortical steroidal hormones in the treatment of purulent meningitis,in order to provide references for clinical rational use. METHODS Dexamethasone used as adjunctive treatment in a 5-month-old boy with purulent meningitis was analyzed and evaluated,including medicinal indication,dosage and course of treatment. RESULTS Cortical steroid hormone should not be used for purulent meningitis routinely,which should weigh the advantages and disadvantages from various aspects to the patients with medicinal indication. The recommended scheme was dexamethasone at a dose of 0.15 mg·kg~(-1),ivgtt,q6h,a total duration of 2-4 days,used before the antimicrobial therapy or simultaneously. CONCLUSION Physicians should be alerted to the role of cortical steroidal hormones in the treatment of purulent meningitis,enhance clinic observing capability to ensure medication safety.

关键词(KeyWords)： 化脓性脑膜炎;地塞米松;皮质固醇类激素
purulent meningitis;dexamethasone;cortical steroidal hormones

Abstract:

Keywords:

基金项目(Foundation):

作者(Author): 赵路,董栋,雷伟
ZHAO Lu,DONG Dong,LEI Wei

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