微粒子酶免分析法测定他可莫司全血浓度结果分析Analyzing of the results of whole blood concentrations of tacrolimus by microparticle enzyme immuno assay
丁少波,胡敏燕
Ding Shaobo;Hu Minyan(Dept. of pharmacy;
摘要(Abstract)：
采用微粒子酶免分析法测定肾移植患者FK5 0 6全血谷浓度。结果发现 :食物、合并用药等均是影响其全血谷浓度的重要因素 ;从免疫抑制效果看 ,术后第 1个月、第 2个月、第 3个月和 3个月以上的理想稳态血药浓度范围分别为 15～ 18ng·ml-1、13～ 16ng·ml-1、12～ 15ng·ml-1、10～ 12ng·ml-1。
Microparticle enizme immuno assay was used for monitoring whole blood concentrations of tacrolimus on renal transplant recipients,the results showed that the optimal therapeutic window of tacrolimus was 15～18ng·ml -1 (less than 1 month after operation),13～16ng·ml -1 (1months～2months),12～15ng·ml -1 (2months～3months),10～12ng·ml -1 (more than 3 months)
关键词(KeyWords)：
他可莫司;微粒子酶免分析法;全血谷浓度
tacrolimus;microparticle enzyme immuno assay;whole blood concentrations
基金项目(Foundation):
作者(Authors):
丁少波,胡敏燕
Ding Shaobo;Hu Minyan(Dept. of pharmacy;
参考文献(References)：
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