今日药学

2019, v.29(01) 25-27

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择期腹腔镜胆囊切除术抗菌药物预防术后感染的回顾性分析
Retrospective Analysis of Antibacterial Drugs for Postoperative Infection in Elective Laparoscopic Cholecystectomy

卢钧雄;王若伦;黄冰冰;段炼;
LU Junxiong;WANG Ruolun;HUANG Bingbing;DUAN Lian;The Second Affiliated Hospital of Guangzhou Medical University;

摘要(Abstract):

目的对择期腹腔镜胆囊切除术围手术期是否预防使用抗菌药物的安全性、可行性以及经济性进行探讨。方法对某院普外科2015年6月~2017年6月间所施行的348例择期腹腔镜胆囊切除术进行回顾性分析。根据围手术期是否预防使用抗菌药物分为两组,用药组和未用药组。对比分析两组的术后感染发生率、住院天数以及药品费用等。结果两组患者术后感染、住院天数差异无统计学意义(P>0.05);未用药组平均药品费用低于用药组,差异有统计学意义(P<0.05)。结论对择期腹腔镜胆囊切除术患者不预防使用抗菌药物不会增加术后感染率和住院天数,并能降低药品总费用,对临床合理用药具有积极意义。
OBJECTIVE To investigate the safety,feasibility,and economics of the use of antibiotics in the perioperative period of elective laparoscopic cholecystectomy. METHODS A retrospective analysis of 348 elective laparoscopic cholecystectomy performed between June 2015 and June 2017 in a general surgery department was performed. According to whether or not to prevent the use of antibiotics in the perioperative period,they were divided into two groups,the drug group and the non-drug group. The incidence of postoperative infections,days of hospitalization,and drug costs were compared between the two groups. RESULTS There was no significant difference in postoperative infection and length of hospital stay between the two groups( P>0.05). The average drug cost in the untreated group was lower than that in the medication group. There was a statistically significant difference between the two groups( P<0.05). CONCLUSION The prevention of use of antibiotics in patients undergoing elective laparoscopic cholecystectomy does not increase the postoperative infection rate and length of hospital stay,and can reduce the total cost of the drug,which is of positive significance for rational clinical use of drugs.

关键词(KeyWords): 择期腹腔镜胆囊切除术;预防使用;抗菌药物;术后感染
elective laparoscopic cholecystectomy;preventive use;antibacterial agents;postoperative infection

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基金项目(Foundation): 国家自然科学基金(81403031)

作者(Author): 卢钧雄;王若伦;黄冰冰;段炼;
LU Junxiong;WANG Ruolun;HUANG Bingbing;DUAN Lian;The Second Affiliated Hospital of Guangzhou Medical University;

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