王小平,郑小清,林羽慧,刘华珍,罗群
WANG Xiaoping,ZHENG Xiaoqing,LIN Yuhui,LIU Huazhen,LUO Qun

• 1:湛江中心人民医院药剂科

摘要(Abstract)：

目的探讨仙灵骨葆与独一味联合应用治疗骨关节炎的临床疗效。方法采用随机对照试验设计,对本院60例骨关节炎患者分组,治疗组(30例)使用仙灵骨葆胶囊、独一味胶囊和钙尔奇D片,对照组(30例)单独使用钙尔奇D片。评估2组的临床疗效及药物安全性。结果 3个月后,治疗组患者的总有效率明显高于对照组,有显著差异(P<0.05),2组的药物安全性均良好。结论仙灵骨葆胶囊联合独一味胶囊治疗骨关节炎,具有良好的临床疗效、无明显毒副作用及可持久应用的特点,两者均为服用方便、安全有效的治疗药物。
OBJECTIVE To explore the clinical effect of Xianling Gubao plus Lamiophlomis Rotata Kudo in treatment of osteoarthritis( OA). METHODS Sixty cases of OA patients were randomly divided into 2 groups. Patients in the treatment group( 30) was treated with Xianling Gubao capsule plus Lamiophlomis Rotata Kudo capsule and Caltrate D tablet,and patients in the control group( 30) were treated with Caltrate D tablet. The clinical effect and security of 2 groups were assessed. RESULTS The total effective rate of the treatment group was significantly higher than that of the control group( P<0.05),the drug safety of 2 groups were good. CONCLUSION Xianling Gubao capsule and Lamiophlomis Rotata Kudo capsule have good clinical curative effect,no obvious side effect and continues application characteristics when they were used to treate OA,and can be both used as a convenient,safe and effective treatment drugs.

关键词(KeyWords)： 仙灵骨葆;独一味;骨关节炎;中药疗法
Xianling Gubao;Lamiophlomis Rotata Kudo;osteoarthritis;treatment with Chinese herbs

Abstract:

Keywords:

基金项目(Foundation):

作者(Author): 王小平,郑小清,林羽慧,刘华珍,罗群
WANG Xiaoping,ZHENG Xiaoqing,LIN Yuhui,LIU Huazhen,LUO Qun

参考文献(References)：

• [1]陆再英,钟南山.内科学[M].北京:人民卫生出版社,2008:903-907.
• [2]中华医学会骨科学分会.骨关节炎诊治指南[J].中国临床医生杂志,2008:28-30.
• [3]方向明,王蓬华,杨强.仙灵骨葆治疗老年性骨质疏松症的疗效观察[J].现代康复,2001,5(3):87.
• [4]吴文,李东风,智喜梅,等.仙灵骨葆对绝经后妇女骨质疏松的防治作用[J].广州中医药大学学报,2005,22(3):191-193.
• [5]茅月娟,吴连国,刘康,等.仙灵骨葆胶囊对骨质疏松病人骨密度改善情况102例[J].中国现代应用药学,2006,23(5):416-418.
• [6]陈熙帆,姜玉祥.仙灵骨葆合乐力对骨质疏松患者骨密度及疼痛的影响[J].中国临床康复,2003,7(27):3769.
• [7]周丕琪,沈霖,杨艳萍,等.中西药两种方法治疗膝关节骨性关节炎的临床观察[J].中国中医骨伤杂志,2002,10(4):23-25.
• [8]董亦明,宋一同.软组织创伤学[M].北京:人民卫生出版社,1990:8.