归秦康骨胶囊质量标准研究Study on Quality Standard of Guiqin Kanggu Capsule
侯伟元,刘坚初,邓鲲鹏
HOU Weiyuan,LIU Jianchu,DENG Kunpeng
摘要(Abstract)：
目的建立归秦康骨胶囊的质量标准。方法采用薄层色谱法(TLC)对当归、秦艽、黄芩进行定性鉴别;采用高效液相色谱法测定芍药苷的含量。结果 TLC斑点清晰、分离度较好,且各阴性对照无干扰;芍药苷的检测浓度在0.064 4~0.644 0μg范围内,与峰面积积分值呈良好的线性关系(r=0.999 9),平均回收率为99.7%,RSD为0.44%(n=6)。结论所建标准可用于归秦康骨胶囊的质量控制。
OBJECTIVE To establish the quality standard of Guiqin Kanggu capsule. METHODS TLC was used for the qualitative identification of Angelisa Sinensis Radix,Gentianae Macrophyllae Radix,Scutellariae Radix. HPLC was used to determine the content of paeoniflorin. RESULTS TLC spots were clear and well-separated without negative interference. The linear range of paeoniflorin was 0.064 4-0.644 μg / L( r = 0.999 9) with an average recovery of 99.7%,and RSD was 0.44%. CONCLUSION The established standard is suitable for the quality control of Guiqin Kanggu capsule.
关键词(KeyWords)：
归秦康骨胶囊;质量标准;芍药苷;薄层色谱法;高效液相色谱法
Guiqin Kanggu capsule;quality standard;Paeoniflorin;TLC;HPLC
基金项目(Foundation):
作者(Author):
侯伟元,刘坚初,邓鲲鹏
HOU Weiyuan,LIU Jianchu,DENG Kunpeng
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