今日药学

2012, v.22(09) 561-563

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Ⅰ类切口手术预防使用抗菌药物调查分析
Analysis of Prophylactic Antibiotics Use in Perioperative Patients with Type Ⅰ Incision Operation

李映辉;胡二文;杜憬生;徐婷;
LI Ying-hui,HU Er-wen,DU Jing-sheng,XU Ting(Department of Pharmacy,Guangdong Provincial Hospital of Chinese Medicine,Guangzhou,Guangdong 510080,China)

摘要(Abstract):

目的了解本院Ⅰ类切口手术预防用抗菌药物使用情况,加强抗菌药物的合理使用。方法采用回顾性调查的方法,随机抽查本院2011-07~2012-02的Ⅰ类切口手术225例,对其预防用抗菌药物情况进行统计分析。结果 225例Ⅰ类切口手术中,128例预防性使用抗菌药物,占56.9%。预防用药均为单用,术前用药1次的47例,占20.9%,24 h内停药的24例,占10.7%,48 h内停药的24例,占10.7%,超过48 h停药的33例,占14.7%。抗菌药物品种分布为4类14种,头孢菌素的应用频次最高(53.8%),其次是青霉素类(6.7%)、林可霉素类(2.7%)、喹诺酮类(0.9%)。结论本院Ⅰ类切口手术预防用抗菌药物存在预防用药比例较高,用药疗程过长,选药不规范,剂量不当的问题,需进一步加强规范管理。
Objective To analyze the prophylactic application of antimicrobial drugs for perioperative patients with type Ⅰ incision operation in order to enhance the rational application of antimicrobial drugs.Methods A total of 225 records of perioperative patients with type Ⅰ incision operation which were filed between Jul.2011 and Feb.2012 were selected randomly from the hospital for retrospective analysis of prophylactic application of antibiotics.Results Among all the 225 cases,128 cases(56.9%) received only one kind of antibiotics.47 cases(20.9%) received a single dosage antibiotics before operation.24 cases(10.7%) received antibiotics in less than 24 h.The proportions of antibacterial regimen within and beyond 48 h were 10.7% and 14.6% respectively,corresponding to 24 cases and 33 cases.14 kinds of antimicrobial agents from 4 categories were used in the operations.The cephalosporin was most frequently used with a rate of 53.8%,followed by penicillins(6.7%),lincomycins(2.7%) and quinolone(0.9%).Conclusion Problem existed in the use of prophylactic antibiotics for patients with type I incision operation in our hospital including: a high proportion of preventive medication,excessive medication regimen,improper chose of antibiotic category and dosage.Thus standardized management on the use of antibiotics needs to be implemented.

关键词(KeyWords): Ⅰ类切口手术;抗菌药物;预防用药;调查分析
type Ⅰ incision;antibiotics;prophylactic use of drug;investigation and analysis

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作者(Author): 李映辉;胡二文;杜憬生;徐婷;
LI Ying-hui,HU Er-wen,DU Jing-sheng,XU Ting(Department of Pharmacy,Guangdong Provincial Hospital of Chinese Medicine,Guangzhou,Guangdong 510080,China)

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