万古霉素个体化给药临床药师指引
何志超,伍俊妍,邱凯锋
摘要(Abstract):
<正>卫生部全国细菌耐药监测网(Mohnarin)数据显示,耐甲氧西林金黄色葡萄球菌(Methicillin-resistant Staphylococcus aureus,MRSA)分离率逐年上升,已成为医院感染重要的革兰阳性细菌[1]。万古霉素作为首个糖肽类抗菌药物,是具有三重杀菌机制的杀菌剂,通过抑制细菌细胞壁的合成、改变细菌细胞膜的通透性以及阻止细菌胞浆内RNA的合成而杀灭细菌,是治疗MRSA感染的首选
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作者(Author):
何志超,伍俊妍,邱凯锋
参考文献(References):
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