叶丹,陈文瑛,肖翔林
YE Dan,CHEN Wen-ying,XIAO Xiang-lin(The First Affiliated Hospital Of Guangzhou Medical College

• 1:广州医学院第一附属医院

摘要(Abstract)：

目的通过医院感染横断面调查了解使用情况。方法床旁调查与查阅住院病历相结合。结果调查住院患者870例,现患率为5.98%,现患例次率为6.44%;感染部位依次是下呼吸道、皮肤软组织、手术伤口;病原体中金黄色葡萄球菌占首位,其次是非发酵革兰阴性杆菌;日使用率为43.33%,头孢菌素类使用频率最高,占46.29%,而使用酶抑制剂的抗生素占首位;外科围手术期预防用药占22.18%,余为术后的治疗或治疗加预防用药。结论住院患者过于集中使用头孢菌素类,分级管理仍然没有到位,术后预防性应用较多,治疗性用药病原学检查标本送检率偏低,需加强抗生素合理应用与规范化管理。
Objective To investigate the situation of antibiotic usage in the cross-sectional study of nosocomial infection.Methods The data was collected through bed-side examination and medical records.Results Among 870 investigated patients,52 patients (5.98%) had 56 cases (6.44%) of infection.The common nosocomail infection sites were the lower respiratory tract,skin and soft tissue,and surgical sites.Staphylococcus aureus was the main pathogen,followed by nonfermenting gram-negative species.The antibiotic usage rate was 43.33%.Cephalosporin was the most frequently used antibiotic,with a usage rate of 46.29%.Antibiotics of enzyme inhibitor in Cephalosporin were the most frequently used.The rate of preoperative antibiotics being use was 22.18%,followed by postoperative usage.Conclusion Cephalosporin was over-used in the inpatients of our hospital.The management of the antibiotics was not satisfactory.The postoperative usage of antibiotics is a little bit higher,while the rate of specimens sent for pathologic examination is low.It is urgent to strengthen the control on rational use and standardized management of antibiotics.

关键词(KeyWords)： 抗生素;医院感染;横断面调查
antibiotics; nosocomail infection; cross-sectional study

Abstract:

Keywords:

基金项目(Foundation):

作者(Author): 叶丹,陈文瑛,肖翔林
YE Dan,CHEN Wen-ying,XIAO Xiang-lin(The First Affiliated Hospital Of Guangzhou Medical College

参考文献(References)：

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• 2李毅萍.住院患者抗菌药物的应用分析.中华医院感染学杂志,2006,16(10):1152-1153.
• 3张延霞,陈晓红,盛燕红,等.手术室抗生素使用分析.中华医院感染学杂志,1998,8(3):179-180.