今日药学

2017, v.27(10) 698-700

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某院头孢菌素类药物皮试情况分析
Analysis of the Skin Test of Cephalosporins in a Hospital

杜鹏强,李兆明,梁明明,司维
DU Pengqiang,LI Zhaoming,LIANG Mingming,SI Wei

摘要(Abstract):

目的选取不同浓度的头孢菌素皮试液,对皮试情况进行分析。方法某院输液中心2016年1月~2016年12月期间,皮试的8种头孢菌素按照皮试液浓度分为两组,A组722例,B组738例;A组使用250μg·mL~(-1)浓度的皮试液,B组使用500μg·mL-1浓度的皮试液,将所得皮试结果进行统计分析。结果 A组皮试总阳性率为2.77%,B组为2.85%,两组比较,差异无统计学意义(P>0.05);A组皮试假阴性率为0.85%,B组为0.14%,两组比较,差异有统计学意义(P<0.05)。结论两种浓度皮试液对皮试结果影响的差异较小,但是考察两组皮试假阴性率,得出B组皮试液浓度更适合。
OBJECTIVE To select different concentrations of cephalosporin skin test solutions,and analyze the skin test results.METHODS In the infusion center of a hospital from January 2016 to December 2016,eight cephalosporins were divided into two groups according to the different concentrations of the skin test solutions-722 cases in group A using 250 μg·mL~(-1) concentration of skin test solution,738 cases in group B using 500 μg·mL~(-1) concentration of skin test solution,and made analysis with the result of skin test.RESULTS The total positive rate of skin test of group A was 2.77%,and group B was 2.85%.There was no significant difference between the two groups(P>0.05).The negative rate of group A was 0.85%,group B was 0.14%.The difference was statistically significant(P<0.05).CONCLUSION The effects of the two skin test solutions on skin test results have small difference,but the two groups of skin tests prove false negative rate,so the B group skin test solution concentration is more suitable.

关键词(KeyWords): 头孢菌素;皮试;分析
cephalosporins;skin test;analysis

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作者(Author): 杜鹏强,李兆明,梁明明,司维
DU Pengqiang,LI Zhaoming,LIANG Mingming,SI Wei

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