基因治疗用腺病毒载体
徐志利,早川尧夫
摘要(Abstract):
腺病毒载体转基因效率高 ,不受靶细胞是否为分裂细胞所限 ;容易制得高滴度病毒载体 ;生物活性评价较简便 ;在临床基因治疗方面有了越来越多的应用。但由于较高的免疫原性 ,导致一过性表达及静脉反复使用困难
关键词(KeyWords):
腺病毒载体;基因治疗;免疫原性;生物活性评价
基金项目(Foundation):
作者(Author):
徐志利,早川尧夫
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