郭洁文,侯小玲,秦乐平
Guo Jiewen(Guangzhou Hospital of Traditional Chinese Medicine;Guangzhou 510130)Hou Xiaoling;Qin Leping(Guangzhou Pharmacy Company of Qixing Ltd Co.Guangzhou 510310);

• 1:广州市中医医院药剂科!广州510130
• 2:广州星群药业有限公司质管部!广州510310
• 3:广州星群药业有限公司质管部!广州510310

摘要(Abstract)：

目的 :研究注射用穿琥宁与 4种抗生素配伍的稳定性。方法 :考察穿琥宁与 4种抗生素在 2 5℃和37℃两种温度条件下 6h内配伍后外观、pH值、微粒数和紫外吸收度。结果 :在上述条件下 ,注射用穿琥宁与头孢唑林钠、头孢拉定、舒巴坦 /头孢哌酮、阿洛西林钠的配伍液外观、pH值、微粒数、紫外吸收度均无明显变化。结论 :2 5℃及 37℃条件下 6h内 ,注射用穿琥宁可与头孢唑林钠、头孢拉定、舒巴坦 /头孢哌酮、阿洛西林钠配伍使用
Objective:To investigated the stability of compatibility of kalii dehydrographolidi succinas injection with four antibiotics.Methods:At 25℃and 37℃ the solutions mixed kalii dehydrographolidi succinas injection with four antibiotics in the aspect ,pH value,particulate counter for injection,UV absorbency and displace of peak were observed within 6 hrs.Results:The solutions mixed kalii dehydrographolidi succinas injection between cefazolin sodium or cefradine or sulbactam sodium/cefoperazone sodium and azlocilline sodium were not significantly changed in the above studied indicatrix.Conclusions:The results suggest that kalii dehydrographolidi succinas injection can mix with cefazolin sodium or cefradine or sulbactam sodium/cefoperazone sodium and azlocilline sodium,and the solutions are unchangeable in above conditions.

关键词(KeyWords)： 穿琥宁;抗生素;配伍;稳定性
Kalii Dehydrographolidi Succinas,Antibiotics,Stability,Compatibility

Abstract:

Keywords:

基金项目(Foundation):

作者(Authors): 郭洁文,侯小玲,秦乐平
Guo Jiewen(Guangzhou Hospital of Traditional Chinese Medicine;Guangzhou 510130)Hou Xiaoling;Qin Leping(Guangzhou Pharmacy Company of Qixing Ltd Co.Guangzhou 510310);

参考文献(References)：

• 1王丽 ,刘宏伟 ,宋铁 ,等 .穿琥宁针剂的研究与临床应用 .中医药信息 . 1998,15 (1) :9～ 10
• 2殷立新 ,胡永福 ,张燕梅 ,等 .穿琥宁注射液在 6种输液中的稳定性考察 .中国医院药学杂志 ,1999,19(2 ) :85～ 86