今日药学

2017, v.27(07) 490-492

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门急诊破伤风抗毒素合理用药分析
Analysis of Rational Drug Use of Tetanus Antitoxin at Outpatient and Emergency Departments

蔡云峰,何秀屏
CAI Yunfeng,HE Xiuping

摘要(Abstract):

目的探讨门诊、急诊处方使用破伤风抗毒素(Tetanus antitoxin,TAT)的合理性。方法抽取某院1 500例应用TAT的门急诊处方,参照国内外的外伤处理指南,并结合患者免疫接种史对伤口破伤风风险进行分类,对TAT应用的合理性进行分析。结果根据统计分析结果,51.68%的门急诊外伤患者没有破伤风风险,不需要注射TAT。结论 TAT存在大量的不合理应用,皮肤过敏试验及注射增加了工作量,脱敏注射增加了医疗风险,需要进行规范。
OBJECTIVE To explore the rationality of drug use of tetanus antitoxin( TAT) in the outpatient and emergency departments. METHODS 1 500 prescriptions of outpatient and emergency departments of a hospital were drawed and the rationality of drug use of TAT was analyzed by referring to the domestic and overseas guidelines for the treatment of trauma and classifying the tetanus risks of trauma combining with patient's history of immunization. RESULTS According to the statistical analysis results,51.68%patients with trauma history had not tetanus risk,thus it's unnecessary to inject TAT. CONCLUSION There are many cases with irrational drug use of TAT; skin allergy test and injection also increased the workload,and desensitization injection may increase medical risk,which needs standardization.

关键词(KeyWords): 破伤风;破伤风抗毒素;合理用药
tetanus;tetanus antitoxin(TAT);rational drug use

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作者(Author): 蔡云峰,何秀屏
CAI Yunfeng,HE Xiuping

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