今日药学

2018, v.28(05) 344-348

[打印本页] [关闭]
本期目录(Current Issue) | 过刊浏览(Past Issue) | 高级检索(Advanced Search)

Meta分析疏肝利胆汤加减比对消炎利胆片治疗慢性胆囊炎的疗效及安全性
Meta-analysis on Effectiveness and Safety of Modified Shuganlidan Decoction and Xiaoyanlidan Pills in Treating Chronic Cholecystitis

陈慕媛;李辉标;唐洪梅;丘振文;李得堂;蔡庆群;
CHEN Muyuan;LI Huibiao;TANG Hongmei;QIU Zhenwen;LI Detang;CAI Qingqun;The First Affiliated Hospital of Guangzhou University of Traditional Chinese Medicine;

摘要(Abstract):

目的评价疏肝利胆汤加减治疗慢性胆囊炎(CC)的有效性和安全性。方法计算机检索CNKI,CBM,Wanfang,VIP、Pub Med、Embase数据库,收集疏肝利胆汤加减比对消炎利胆片治疗慢性胆囊炎的随机对照试验文献。由两名研究者进行资料提取和文献质量评价,采用Rev Man 5.3软件进行Meta分析。结果本研究共纳入6个随机对照试验(RCT),共计551例患者。Meta分析结果显示,对比消炎利胆片,疏肝利胆汤加减明显提高慢性胆囊炎的临床有效率[OR=4.66,95%CI(2.74,7.91),P<0.000 01],试验组与对照组在临床症状改善方面比较差异无统计学意义。结论与消炎利胆片比较,疏肝利胆汤加减对慢性胆囊炎有更好的疗效,但由于纳入文献质量较低,且文献数量偏少,需进一步开展更多高质量、大样本的随机双盲试验。
OBJECTIVE To systematically evaluate the clinical efficacy and safety of Modified Shuganlidan decoction in treating chronic cholecystitis( CC). METHODS Randomized control trials investigated Shuganlidan decoction comparing with Xiaoyanlidan pills in chronic cholecystitis were identified by searching CNKI,CBM,VIP,Wanfang,Pub Med and Embase. Meta-analysis was performed using Rev Man 5. 3 software. RESULTS Six RCTs involving 551 patients were included. The Meta-analysis showed that compared with Xiaoyanlidan pills,Shuganlidan decoction significantly improved the clinical effective rate [OR = 4. 66,95% CI( 2. 74,7.91),P<0.000 01],but not for clinical symptoms. CONCLUSION Shuganlidan decoction are more effective in the treatment of chronic cholecystitis compared to Xiaoyanlidan pills. Future trials with high quality and large samples should be performed to confirm this conclusion.

关键词(KeyWords): 疏肝利胆汤;消炎利胆片;慢性胆囊炎;Meta分析
shuganlidan decoction;Xiaoyanlidan pills;chronic cholecystitis;Meta-analysis

Abstract:

Keywords:

基金项目(Foundation): 广东省医院药学研究基金(2016A08)

作者(Author): 陈慕媛;李辉标;唐洪梅;丘振文;李得堂;蔡庆群;
CHEN Muyuan;LI Huibiao;TANG Hongmei;QIU Zhenwen;LI Detang;CAI Qingqun;The First Affiliated Hospital of Guangzhou University of Traditional Chinese Medicine;

Email:

DOI:

参考文献(References):

扩展功能
本文信息
服务与反馈
本文关键词相关文章
本文作者相关文章
中国知网
分享