今日药学

2021, v.31(05) 321-333+338

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玉米肽的研究与应用进展
Progress on the Research and Application of Corn Peptides

闫昌誉;李怡芳;李晓敏;李家炜;余宗盛;高业成;陈小娟;何蓉蓉;高昊;栗原博;
YAN Changyu;LI Yifang;LI Xiaomin;LI Jiawei;YU Zongsheng;GAO Yecheng;CHEN Xiaojuan;HE Rongrong;GAO Hao;KURIHARA Hiroshi;Perfect Life Sciences Research Institute Co.Ltd.;Perfect (Guangdong) Daily Necessities Co.,Ltd.;Institute of Traditional Chinese Medicine and Natural Products,School of Pharmacy,Jinan University;

摘要(Abstract):

玉米黄粉也叫玉米蛋白粉,是玉米淀粉加工产生的主要副产物,含有丰富的蛋白质资源。玉米肽是玉米蛋白粉经酶解或酵解制备的小分子多肽物质,已于2010年被国家卫生部批准为新资源食品。大量研究表明玉米肽具有多种生物活性如醒酒护肝、抗氧化、抗高血压、降血糖和降血脂等。随着蛋白分析技术的发展,许多玉米肽活性氨基酸序列被逐渐鉴定出来。玉米肽的研究和产业化应用,有益于提高玉米产业的经济和社会效益。本文对玉米肽的制备、分离纯化、结构鉴定、生物活性以及产业化应用等进行了概述,旨在为玉米肽的进一步开发利用提供有益的依据。
Corn gluten meal is the main by-product of corn starch processing with a lot of protein.Corn peptide is prepared by enzymatic hydrolysis or fermentation of corn gluten meal, and it was approved as a new resource food by the Ministry of Health in 2010.Numerous studies have shown that corn peptide has a variety of biological activities such as facilitation of alcohol metabolism, hepatoprotection, anti-oxidation, anti-hypertension, anti-hyperglycemia and anti-hyperlipemia.With the development of protein analysis technology, many active amino acid sequences of corn peptides have been gradually identified.The research and industrial application of corn peptide are beneficial for improvement in economic and social values of the corn industry.This article summarizes the preparation, separation and purification, structure identification, biological activities and industrial application of corn peptide to provide a useful basis for the further development and utilization of corn peptide.

关键词(KeyWords): 玉米蛋白粉;玉米肽;活性序列;制备方法;生物活性;产业应用
corn gluten meal;corn peptide;active sequence;preparation method;biological activity;industrial application

Abstract:

Keywords:

基金项目(Foundation): 国家自然科学基金(U1801284);; 中山市院士工作站建设项目(中山科发[2019]187号);; 中山市第八批创新创业科研团队项目(CXTD2020003)

作者(Author): 闫昌誉;李怡芳;李晓敏;李家炜;余宗盛;高业成;陈小娟;何蓉蓉;高昊;栗原博;
YAN Changyu;LI Yifang;LI Xiaomin;LI Jiawei;YU Zongsheng;GAO Yecheng;CHEN Xiaojuan;HE Rongrong;GAO Hao;KURIHARA Hiroshi;Perfect Life Sciences Research Institute Co.Ltd.;Perfect (Guangdong) Daily Necessities Co.,Ltd.;Institute of Traditional Chinese Medicine and Natural Products,School of Pharmacy,Jinan University;

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