今日药学

2015, v.25(09) 669-672

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2014年某综合医院药品不良反应报告分析
Analysis of ADR Case Reports of A General Hospital in 2014

孙萍萍,吴海燕,陈杰
SUN Pingping,WU Haiyan,CHEN Jie

摘要(Abstract):

目的监测本院不良反应(ADR)发生情况,提高本院合理用药水平。方法对2014年上报的221例ADR报告进行统计分析。结果 ADR报告72%来自于临床药师;年龄大于60 a的患者更易发生药品不良反应;抗感染药物的ADR报告例数居第1位;静脉滴注药物引发的ADR占52.47%;不良反应的主要类型为肝胆系统损害,其次为皮肤及其附件损害。结论药物不良反应与多种因素有关,加强药物不良反应监测有助于保障患者用药安全。
OBJECTIVE To promote rational drug application by monitoring adverse drug reactions( ADR) in a general hospital.METHODS All the ADR case reports of the hospital in 2014 were collected and analyzed. RESULTS 72% ADR case reports came from clinical pharmacists. Patients who older than 60 years were prone to occur ADR. Most of ADR cases were involved in antibiotic drugs; 52. 47% of ADR cases were induced by iv drip. The main types of ADR were liver and skin injuries. CONCLUSION Adverse drug reactions are related to multiple factors,ADR monitoring should be strengthened in clinic to ensure drug safety.

关键词(KeyWords): 不良反应;合理用药
adverse drug reactions;rational drug application

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作者(Author): 孙萍萍,吴海燕,陈杰
SUN Pingping,WU Haiyan,CHEN Jie

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