方娆莹,张电光,陈锡炎,吴耀光
FANG Raoying,ZHANG Dianguang,CHEN Xiyan,WU Yaoguang

• 1:广东省生物制品与药物研究所

摘要(Abstract)：

目的建立气相色谱法同时测定心宝丸中冰片、桂皮醛、麝香酮的含量。方法以改性聚乙二醇为固定相,氮气为载气,FID检测,检测口温度为250℃,柱温为程序升温。结果在该色谱条件下,冰片、桂皮醛和麝香酮3组分的分离度和线性关系良好,平均加样回收率(n=6)分别为99.8%(RSD=1.34),101.4%(RSD=0.87),96.5%(RSD=1.89)。结论本法简便、快速,准确性和重复性好,可用于心宝丸的质量控制。
OBJECTIVE To separate and determine the content of synthetic borneol,cinnamaldehyde and muscone in Xinbao pills.METHODS The GC system was consisted of glass column,with modified PEG as the stationary phase,nitrogen as the carrier gas,FID detector at 250 ℃ and programmed heating method. RESULTS The resolution and linearity of synthetic borneol,cinnamaldehyde and muscone were good with the recovery rate of synthetic borneol at 99.8%( RSD = 1.34),cinnamaldehyde 101.4%( RSD= 0. 87),muscone 96. 5%( RSD = 1. 89),respectively. CONCLUSION The method is convenient,rapid,accurate and reproducible,and it can be used to control the quality of Xinbao pills.

关键词(KeyWords)： 心宝丸;冰片;桂皮醛;麝香酮;含量测定
Xinbao pills;synthetic borneol;cinnamaldehyde;assay

Abstract:

Keywords:

基金项目(Foundation): 广东省中医药管理局建设中医药强省科研课题(20142010)

作者(Author): 方娆莹,张电光,陈锡炎,吴耀光
FANG Raoying,ZHANG Dianguang,CHEN Xiyan,WU Yaoguang

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