樊祥伟,陈凯云,李静,帅芳源,张翰弘,于雪峰
FAN Xiangwei,CHEN Kaiyun,LI Jing,SHUAI Fangyuan,ZHANG Hanhong,YU Xuefeng

• 1:南昌大学第四附属医院
• 2:四川大学华西口腔医学院

摘要(Abstract)：

目的观察康脉通预防骨科大手术术后下肢深静脉血栓(DVT)形成的疗效及安全性。方法选取某院2016年3月~2017年3月行骨科大手术患者120例。随机分为康脉通组、低分子肝素组及利伐沙班组,每组40例。比较康脉通组与低分子肝素组、利伐沙班组下肢静脉血栓的发生率,术中、术后出血情况,以及D-二聚体、纤维蛋白原变化情况。结果康脉通组与低分子肝素组、利伐沙班组比较,术后下肢深静脉血栓发生率差异无统计学意义(P>0.05),无明显出血事件发生;术中、术后出血情况,以及D-二聚体、纤维蛋白原变化情况差异无统计学意义(P>0.05)。结论康脉通在预防骨科大手术术后下肢DVT形成方面具有良好的疗效及安全性。
OBJECTIVE To observe the effects of Kangmaitong in prevention of deep venous thrombosis(DVT) after large orthopedic surgery.METHODS 120 patients after large orthopedic surgery between March 2016 to March 2017 of a hospital were selected,they were divided into Kangmaitong group,Rivaroxaban group and low molecular weight heparin(LMWH) group.Compared the occurrence rate of DVT,bleeding and D-Dimer,fibrinogen before and after operation between Kangmaitong group with Rivaroxaban group and LMWH group.RESULTS The occurrence rate of DVT,bleeding and D-Dimer,fibrinogen before and after operation were no obviously change between Kangmaitong group with Rivaroxaban group and LMWH group(P>0.05).No bleeding events occurred.CONCLUSION Kangmaitong can prevent DVT after large orthopedicsurgery effectively and safely.

关键词(KeyWords)： 康脉通;骨科大手术;深静脉血栓
Kangmaitong;large orthopedic surgery;deep venous thrombosis

Abstract:

Keywords:

基金项目(Foundation): 江西省教育厅科学技术研究项目(150280);; 江西省科技计划项目(20141BBG70055)

作者(Author): 樊祥伟,陈凯云,李静,帅芳源,张翰弘,于雪峰
FAN Xiangwei,CHEN Kaiyun,LI Jing,SHUAI Fangyuan,ZHANG Hanhong,YU Xuefeng

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