今日药学

2017, v.27(03) 190-193

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某院肾移植住院患者免疫抑制剂使用情况分析
Investigation and Analysis of the Use of Immunosuppressive Agents of 74 Renal Transplantation Patients

郑妙玲;
ZHENG Miaoling;The Forth Affiliated Hospital of Guangzhou Medical University;

摘要(Abstract):

目的了解某院肾移植住院患者免疫抑制剂的使用情况,为寻找更有效的免疫抑制剂治疗方案以促进临床合理用药并提高肾移植患者的生存质量提供依据。方法回顾性查阅某院2015年肾脏移植病历74份,记录患者住院期间原发疾病、肾移植术后并发症和排斥反应、用药情况和住院费用等信息,并对患者免疫抑制剂的使用情况进行分析。结果患者的平均年龄为(42.51±12.18)a;平均住院日为(25.95±13.63)d;平均总药费约为45 617.91元;免疫抑制剂平均费用为21 737.73元,占平均总药费的47.65%;免疫抑制剂使用频率排序前3位的品种分别为糖皮质激素、吗替麦考酚酯、环孢素A。结论肾移植住院患者免疫抑制剂费用占比较大,且多为联合用药,寻找更有效、不良反应更少、价格更低的免疫抑制治疗方案对提高肾移植患者的生存质量和挽救更多肾功能衰竭患者的生命具有重要意义。
OBJECTIVE To investigate the usage of immunosuppressive agents of renal transplantation patients in a hospital,so as to looking for more effective immunosuppressive therapy,promoting clinical rational drug use and improving the quality of renal transplantation patients survival. METHODS The medical records of 74 kidney transplantation in a hospital in 2015 were reviewed retrospectively. The usage of immunosuppressant was analyzed by collecting the imformation of primary disease,complications after renal transplantation,the information of rejection,medication and the hospitalization expenses. RESULTS The average age of patients was( 42.51±12.18) years; the average stay was( 25.95±13.63) days; the average total cost of drugs was 45617.91 yuan; the average cost of immunosuppressants was about 21 737.73 yuan,accounting for an average of 47.65% of the total drugs cost. The most frequently used immunosuppressive agents were Glucocorticoid,Mycophenolate Mofetil,Ciclosporin A. CONCLUSION The immunosuppressive agents were mainly used on the renal transplantation patients and the drugs were always used in combination. It is important to find a more effective,less adverse and cheaper treatment plan for the kidney transplantation patients in order to save more lives and to improve the quality of life.

关键词(KeyWords): 肾移植;免疫抑制剂;使用情况
Renal transplantation;Immunosuppressive agent;Usage

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作者(Author): 郑妙玲;
ZHENG Miaoling;The Forth Affiliated Hospital of Guangzhou Medical University;

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