杨水源,童艳丽,梅清华,卢慧勤
YANG Shuiyuan,TONG Yanli,MEI Qinghua,LU Huiqin

• 1:广东省第二人民医院药学部

摘要(Abstract)：

目的了解依替米星在某院急诊科的使用情况,为临床合理用药提供依据。方法抽取2015年1月~2015年12月共3720张使用依替米星的急诊处方,进行用药合理性分析。结果 3 720张处方中,适应证不适宜571例,占15.35%;用法用量不适宜27例,占0.73%;联用不适宜29例,占0.78%;诊断书写不全7例,占0.19%。结论依替米星在急诊科存在不合理使用的情况,医院应进一步规范临床医师对抗菌药物的使用。
OBJECTIVE In the present study,we aim to analyze the irrational use of etimicin in emergency department,and provide the basis for clinical rational drug use. METHODS A total of 3 720 etimicin prescriptions in emergency treatment were collected from January 2015 to December 2015 in a hospital, and the irrational usage was analyzed. RESULTS Of 3 720 prescriptions,571( 15.35%) were no indications for drug use,27( 0. 73%) were unsuitable usage and dosage,29( 0. 78%) were unreasonable combination therapy,and 7( 0.19%) were incomplete prescription writing. CONCLUSION Irrational use of etimicin exist in our hospital,and the clinicians should follow the rational principles to standardize the use of antibiotics.

关键词(KeyWords)： 依替米星;抗菌药物;合理性
etimicin;antibacterial drugs;rationality

Abstract:

Keywords:

基金项目(Foundation): 广东省医学科研基金项目(A2014160)

作者(Author): 杨水源,童艳丽,梅清华,卢慧勤
YANG Shuiyuan,TONG Yanli,MEI Qinghua,LU Huiqin

参考文献(References)：

• [1]陈新谦,金有豫,汤光.新编药物学[M].北京:人民卫生出版社,2011:70-75.
• [2]盛淑琦,吴昊姝.浅析硫酸依替米星注射剂的不良反应与安全性[J].海峡药学,2013,25(10):180-183.
• [3]卫生部.关于做好全国抗菌药物临床应用专项整治活动的通知[S].2011.
• [4]卫生部.卫生部办公厅关于继续深入开展全国抗菌药物临床应用专项整治活动的通知[S].2012.
• [5]陈江,周广青.氨基糖苷类药物的不良反应及合理用药[J].临床合理用药杂志,2013,6(2):65.
• [6]樊珍和.氨基糖苷类抗生素1次/d给药方案研究概况[J].中国医药指南,2010,8(24):25-26.
• [7]陈新谦,金有豫,汤光.新编药物学[M].北京:人民卫生出版社,2011:15.
• [8]Lee S I,Lee J H,Lee S C,et al.Calcium and neostigmine antagonize gentamicin,but augment clindamycin-induced tetanic fade in rat phrenic nerve-hemidiaphragm preparations[J].Journal of anesthesia,2008,22(4):385-390.
• [9]刘明姬,吴昌彬,袁宝龙,等.氨基糖苷类抗生素对兔神经肌肉功能的抑制作用[J].中山大学学报,2003,24(6):573-576.
• [10]刘晓鸿.克林霉素与依替米星联用致双手紫绀1例[J].中国药物警戒,2013,10(5):318.