今日药学

2020, v.30(04) 279-281

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临床药师参与1例糖尿病患者胰岛素脱敏方案优化的病例分析
Clinical Pharmacists' Participation in Optimization of Sulin Desensitization in A Diabetic Patient

边原;熊堉;李文渊;龙恩武;
BIAN Yuan;XIONG Yu;LI Wenyuan;LONG Enwu;Department of pharmacy,Sichuan Academy of Medical Sciences,Sichuan Provincial People's Hospital,Affiliated Hospital of University of Electronic Science and Technology of China,Personalized Drug Therapy Key Laboratory of Sichuan Province;School of Medicine,University of Electronic Science and Technology of China;

摘要(Abstract):

目的为临床药师参与胰岛素过敏患者的脱敏方案优化提供参考。方法临床药师参与了1例胰岛素过敏患者脱敏方案的实施与优化过程,分析其过敏类型,制定脱敏方案并实施全程化的药学监护。结果该患者使用口服降糖药疗效不佳,且对胰岛素制剂过敏,临床药师建议采用胰岛素脱敏治疗。通过皮内注射实验决定采用生物合成人胰岛素进行脱敏治疗,患者脱敏成功,经过治疗后血糖水平达标并出院。结论临床药师可在胰岛素过敏患者脱敏方案制定中协助临床医师优化方案并发挥积极的作用。
OBJECTIVE To provide reference for clinical pharmacists participation in optimization of insulin desensitization in a diabetic patient. METHODS The clinical pharmacist participated in the implementation and optimization of insulin desensitization for a patient with insulin allergy, analyzed the type of allergy, formulated a desensitization program, and implemented integrated pharmaceutical care. RESULTS The patient had poor efficacy with oral hypoglycemic drugs and was allergic to insulin. The clinical pharmacist recommended insulin desensitization. Through intradermal injection,clinical pharmacist decided to use biosynthetic human insulin for desensitization.Finally,the patient was successfully desensitized. After treatment,his blood glucose level was normal and he was discharged from the hospital. CONCLUSION Clinical pharmacists can play an active role in assisting clinicians in optimizing the formulation of desensitization schemes for patients with insulin allergy.

关键词(KeyWords): 临床药师;糖尿病;胰岛素脱敏
clinical pharmacist;diabetes;insulin desensitization

Abstract:

Keywords:

基金项目(Foundation): 国家临床重点专科建设项目(30305030698);; 四川省省级公益性科研院所基本科研业务专项课题(2018YSKY0017);; 四川省人民医院院级科研基金临床研究及转化项目(2018LY09)

作者(Authors): 边原;熊堉;李文渊;龙恩武;
BIAN Yuan;XIONG Yu;LI Wenyuan;LONG Enwu;Department of pharmacy,Sichuan Academy of Medical Sciences,Sichuan Provincial People's Hospital,Affiliated Hospital of University of Electronic Science and Technology of China,Personalized Drug Therapy Key Laboratory of Sichuan Province;School of Medicine,University of Electronic Science and Technology of China;

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