冯双清,詹云丽,梁建翁,林宇
FENG Shuangqing,ZHAN Yunli,LIANG Jianweng,LIN Yu

• 1:惠州市第六人民医院
• 2:惠州市药品不良反应监测中心
• 3:广东省药品不良反应监测中心

摘要(Abstract)：

目的通过开展基本药物不良反应主动监测与合理用药分析,了解不良反应发生率,并进一步规范临床合理用药,为安全用药提供临床依据。方法选择本院4个基本药物品种开展ADR主动监测,并从用药过量、理化配伍禁忌、溶媒选择不合理、超适应证使用、药物选用不当和重复用药等方面进行分析。结果 2 664例监测病例中共发生5例ADR,ADR累计发生率为0.19%;筛选不合理处方139份,不合理处方的比例为5.2%。结论医疗机构应重视基本药物临床使用安全性,关注临床不合理用药与ADR发生之间的关系。
OBJECTIVE To understand the incidence of adverse drug reactive( ADR) by ADR intensive monitoring of the essential medicine in the hospital,and to provide clinical reference for the medicine safety. METHODS The data of 4 essential medicines selected on ADR intensive monitoring was analyzed by over dosage,incompatibility of drugs in prescription,improper choice of solvents and repeated administration. RESULTS There were 5 ADRs occurred in 2 664 cases. The overall incidence of ADR was0. 19%. 139 unreasonable prescriptions were sift out. The unreasonable prescriptions account for 5. 2% of the total prescriptions.CONCLUSION The hospital should attach great importance to the clinical safety of essential medicine,also pay attention to the relevance of unreasonable prescription and ADRs.

关键词(KeyWords)： 基本药物;合理用药;药品不良反应
essential medicine;rational application of drug;adverse drug reaction

Abstract:

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基金项目(Foundation):

作者(Author): 冯双清,詹云丽,梁建翁,林宇
FENG Shuangqing,ZHAN Yunli,LIANG Jianweng,LIN Yu

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