今日药学

2015, v.25(05) 372-374

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某院2011~2013年再生障碍性贫血患者院内感染分析
Anlysis of Nosocomial Infection in Patients with Aplastic Anemia

庾杰华
YU Jiehua

摘要(Abstract):

目的探讨再生障碍性贫血患者院内感染易感因素及预防措施。方法对本院2011~2013年的再生障碍性贫血患者发生院内感染情况进行回顾性分析。结果再生障碍性贫血患者院内感染率为36.0%,极重型再生障碍性贫血患者为84.2%,感染好发部位为呼吸道,其次是口腔、胃肠、皮肤等,白细胞计数小于1.5×109/L的患者院内感染率明显高于白细胞计数大于1.5×109/L;住院时间小于30 d的患者院内感染率明显低于住院时间超过30 d的患者。结论再生障碍性贫血患者易发生院内感染,感染最常见部位为呼吸道,住院时间过长,白细胞数过低,均易增加感染机会,应加强预防措施,尽量减少院内感染,提高患者生存率。
OBJECTIVE To assess the factors in uencing the nosocomial infection in patients with aplastic anemia( AA),and investigate the preventive measures. METHODS Infection control committee records were reviewed to identify the cases between 2011 and 2013. Only the AA patient was included in the study. RESULTS A total of 189 patients with AA were identi ed. The infection rate was 36. 0%,and 84. 2% for severe ones. The commonly seen infected part was respiratory tract,then was oral cavity,gastrointestinal,skin,and so on. The infection in AA patients with WBC below 1. 5 × 109/ L was higher than those with higher WBC.Patients with long-term( > 30 d) hospitalization were more easily subjected to the infection. CONCLUSION Patients with AA are at high risk for nosocomial infection. Respiratory tract is the most commonly infected part. Long-term hospitalization and lower WBC can both increase the infection rate. To improve the survival rate,it is important to strengthen preventive measures of the infection.

关键词(KeyWords): 再生障碍性贫血;感染;数据分析
aplastic anemia;infection;data analysis

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作者(Author): 庾杰华
YU Jiehua

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