治疗药物监测概况及研究进展Overview and progress of therapeutic drug monitoring
李欣,赵立子,黄民
LI Xin,ZHAO Li-zi,HUANG Min (Institute of Clinical Pharmacology
摘要(Abstract):
通过查阅有关书籍和近年国内外的文献资料,回顾治疗药物监测(TDM)的发展与现状,介绍目前进行TDM的药物种类和常用技术方法,展望遗传药理学在个体化用药中的应用前景。未来的治疗药物监测模式是传统模式和药物遗传学监测相结合,进一步完善个体给药方案的制定。
After review the development and situation of TDM,we describe the variety of drugs which need TDM and populat monitoring methods,also prospect the foreground of pharmacogenetics in the individualized medication.The mode of TDM in the future is the combination of traditional methods and pharmacogenetics.
关键词(KeyWords):
治疗药物监测;色谱法;免疫分析法;遗传药理学
therapeutic drug monitoring;chromatography;pharmacogenetics;immunoassay
基金项目(Foundation):
作者(Author):
李欣,赵立子,黄民
LI Xin,ZHAO Li-zi,HUANG Min (Institute of Clinical Pharmacology
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