双解退热口服液的药理作用Pharmacological studies on the Shuangjie Tuire Oral Liquid
路筱涛,陶涛
Lu Xiaotao;Tao Tao (Xian-Janssen Pharmaceutical Ltd;
摘要(Abstract)：
目的 探讨双解退热口服液解热、镇痛、抗炎的药理作用。方法 大鼠口服双解退热口服液,以阿斯匹林片为阳性对照,观察该药品对大鼠发热体温及化学法和热板法所致小鼠疼痛反应的影响;以醋酸强的松龙为阳性对照,观察该药品对蛋清所致大鼠足踝关节肿胀率的抑制作用的影响。结果 双解退热口服液能明显降低发热大鼠体温,且具有镇痛作用,此解热镇痛作用类似阿斯匹林;同时还能明显抑制蛋清所致大鼠足踝关节肿胀,具有抗炎作用。结论 本研究为该口服液临床作为解热、镇痛、抗炎药应用提供了实验依据。
Objetive To supply basic research materials for clinical application of Shuangjie Tuire Oral Liquid. Methods Effects on eliminating-heat, relieving pain and restrain swelling of Shuangjie Tuire Oral Liquid were tested after oral administration Results The drug possesses the actions of eliminating-heat, relieving pain, and anti-inflammation. Conclusion The studies apply basic research materials for clinical application of this drug.
关键词(KeyWords)：
双解退热口服液;药理作用
Shuangjie Tuire Oral Liquid; pharmacological activity
基金项目(Foundation):
作者(Authors):
路筱涛,陶涛
Lu Xiaotao;Tao Tao (Xian-Janssen Pharmaceutical Ltd;