三七极细粉制备工艺研究Study on Preparation Process of Micropowder of Notoginseng
谢汉凤,张清民
XIE Hanfeng,ZHANG Qingmin
摘要(Abstract)：
目的采用振动式药物超微粉碎机对三七药材进行超微粉碎工艺研究,并研究超微粉碎对其粉末质量的影响。方法通过单因素和正交试验设计,对三七粉末粒径分布进行统计分析,确定超微粉碎工艺参数。与粗粉进行对比研究,分别测定流动性、吸湿性、浸出物含量及有效成分含量,评价三七极细粉与粗粉的质量差异。结果优选工艺为粗碎选择20目筛网,超微粉碎时间45 min,超微粉碎温度-10℃~-5℃,所得的三七极细粉粒度分布均匀,浸出物含量及有效成分含量均比粗粉高,但超微粉碎技术带来了流动性变差、吸湿性增强等新问题。结论三七药材超微粉碎后粒径减小提高了生物利用度,同时降低了流动性、增强了吸湿性,在应用中应综合考虑。
OBJECTIVE Optimization on superfine pulverization process of medicinal notoginseng by vibrating drug ultrafine grinder is investigated in this paper,and the effect of superfine pulverization on its powder quality is also studied. METHODS A single factor and an orthogonal rotation experiments were designed to analyzed the particle distribution of notoginseng and determine the technological parameters of superfine pulverization. Compared with coarse powder,the flowability,moisture absorption,extraction content and effective component content were determined respectively in order to evaluate the quality difference between micropowder and coarse powder of notoginseng. RESULTS The optimizing process was obtained with the mesh screen of 20,the superfine pulverization of 45 min and the superfine pulverization temperature of -10 ℃ to -5 ℃.The superfine powder of notoginseng showed that the particle size of was uniform,the content of extraction and effective component content were higher than coarse powder,but superfine pulverization technology brings new problems,such as poor mobility and moisture absorption enhancement. CONCLUSION The decrease of particle size after superfine pulverization of notoginseng medicinal materials improves its bioavailability,reduces fluidity and increases moisture absorption,that should be considered in the application.
关键词(KeyWords)：
三七药材;极细粉;制备工艺;超微粉碎
notoginseng medicinal materials;micropowder;preparation process;superfine pulverization
基金项目(Foundation): 博罗县科技计划项目(2015B011502004)
作者(Author):
谢汉凤,张清民
XIE Hanfeng,ZHANG Qingmin
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